TRAPS*

web TRAPS
Epidemiology

Blue gender

Gender ratio

1 : 1

Blue incidence

Prevalence

1/106

Disease presentation

Genetic grounds

The disease displays an autosomal dominant inheritance (i.e., receiving the gene from only one parent is enough to develop the disease). The involved mutated gene is TNFRSF1a coding for type 1A receptor to TNF.

Main clinical symptoms

picto feverElevated fever with chills

picto skin rashUrticary-like cutaneaous lesions

picto Abdo painAbdominal pain

Biological signs

Unconclusive

Therapy

  • Anti-IL-1 (e.g. Anakinra, Canakinumab)
  • Corticosteroids
  • Anti-TNFα (Etanercept)
  • Anti-IL-6 (e.g. Tocitizumab)

*Tumor necrosis factor Receptor-Associated Periodic Syndrom