Video presentation

Takayasu disease

Disease presentation

The disease is a systemic vasculitis affecting large/medium sized blood vessels. Its diagnosis mainly relies on imaging of arterial lesions.

Main clinical symptoms

Fever as an early phase sign with excessive fatigue, involuntary weight loss, general weakness

Vessel inflammation (and poor circulation): inflamed aorta and subsequent arteries leading to coldness, cyanosis, pain in hands and feet, headache, claudication

Biological signs

Increase in C-reactive protein (CRP) for 50% of patients

Absence of AntiNeutrophil Cytoplasmic Antibodies (ANCA)

Therapy